Monitor Configuration
In MLM-AI, a Monitor is where users define how to produce results to be screened in a Review. Among other things, a Monitor defines:
  • The search terms to include in the search for the product of interest.
  • What literature sources to search.
  • How often should results be produced.
  • What teams will perform reviews.
A summary of configured monitors is seen from the Drug Management page:

Creating Monitors

To create a new monitor, click the "+ Add Monitor" button, this will open the setup page. Alternatively, or chose to Copy the definitions from an existing monitor if you wish to replicate existing configuration settings.
Give your new monitor a name:
Search Terms
To add search terms just enter the product name or compound in the synonym keyword field. This will auto-populate a list of synonyms to choose from. You can select which dictionaries to search (MeSH and DrugBank are enabled by default).
To include terms in your search, click on the desired selections and then click "Add Selected". Or check the "Select All" checkbox to include the entire list.
Your chosen terms will appear in the "Chosen Search Terms" box. This is the final list that will be used when searching for the product. The search strategy is OR-based.
To sanity check your search terms, click on "View this search in PubMed" to open up a PubMed query that includes all the search terms (OR-based query).
MLM-AI automatically loads data from various literature sources. Select which ones to use when searching with this monitor:
Monitors can be configured to run periodically and produce results automatically, or run only ad-hoc from a user request. When a monitor runs on a schedule, "Day Zero" is the weekday when results will be produced (if monitor runs weekly). "ETA for Completion" specifies a number of days for screening completion, once results are presented.
If you don't want your monitor to run on a schedule, just specify to run the search "On Request".
Team Assignment
This section assigns teams to screening stages, giving users permissions to update decisions on incoming abstracts.
Learn more about team and user setup on: Team and User Management
Special Situations and Exclusions
When users save their screening decisions, they can select categories for exclusions and special situations. The selections are multi-choice and come pre-populated with values typical for ICSR screening.
The values can be configured per your workflow: existing entries can be removed and custom ones added as needed via the "Add Custom" box.

Monitor Options

Additional settings control monitor behavior on automatic screening and date searches:
Auto-Exclude by tags
  • Auto-exclude results with tag: Animal/In-Vitro - When an article receives the "Animal/In-Vitro" tag it is automatically screened as an Invalid ICSR with the corresponding exclusion.
  • Auto-exclude results without tag: Suspect AE - Articles without the Suspect AE tag are auto-excluded with "missing adverse event" as corresponding exclusion.
  • Auto-exclude results without tags: Identifiable patient/suspected case - if an article was not predicted as "suspected case" or "identifiable patient", it is automatically screened as Invalid ICSR with the "missing patient" exclusion.
  • Automatically exclude duplicate articles - Articles with a detected duplicate on results for the same monitor are automatically screened as Invalid ICSR with the Duplicate exclusion.
How to search for dates
The following settings control how dates are applied on search results:
  • Include abstracts found by publication date - searches the same date range matching the publication date. This option is useful to maintain correspondence to existing manual search strategies.
  • Discard publication dates older than 60 days - if the difference of an article first seen date and publication date is older than 60 days, results are discarded. This option is useful to avoid spurious results from "blanket" publication of journals going back many years.
See also date handling in the MLM-AI Concepts guide for more details.

Disabling Monitors

Monitors can be disabled from the Monitor Summary page. This will stop scheduled monitors from producing reviews. Already generated reviews or reviews in progress are not affected.